Temozolomide( Purity > 99% by HPLC)

Product Name: Temozolomide
 CAT#: A-2223

Request Temozolomide
 Synonym:US brand names: Methazolastone; Temodar. Foreign brand name: Temodal Abbreviation: TMZ. Code names: CCRG-81045; M & B 39831; RP-46161; SCH 52365. ,

Temozolomide Chemical Structure
Temozolomidechemical structure

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IUPAC/Chemical name:

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Biological Activity
Temozolomide is a triazene analog of dacarbazine with antineoplastic activity. As a cytotoxic alkylating agent, temozolomide is converted at physiologic pH to the short-lived active compound, monomethyl triazeno imidazole carboxamide (MTIC). The cytotoxicity of MTIC is due primarily to methylation of DNA at the O6 and N7 positions of guanine, resulting in inhibition of DNA replication. Unlike dacarbazine, which is metabolized to MITC only in the liver, temozolomide is metabolized to MITC at all sites. Temozolomide is administered orally and penetrates well into the central nervous system
Technical Data

Purity: >99%
Chemical Formula:C6H6N6O2
Molecular Weight:194.15
Temozolomide MSDSTemozolomide CoA

IUPAC/Chemical name:3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide.
Canonical SMILES:

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