Idelalisib( Purity > 99% by HPLC)

Product Name: Idelalisib
 CAT#: A-2115

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 Synonym: Idelalisib; CAL-101; CAL 101; CAL101; GS-1101; GS 1101; GS1101 ,

Idelalisib Chemical Structure
Idelalisibchemical structure

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IUPAC/Chemical name:

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Biological Activity
Idelalisib, also known as CAL-101, is a PI3K-delta inhibitor with potential immunomodulating and antineoplastic activities. CAL-101 inhibits the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K-delta is expressed primarily in hematopoietic lineages. The targeted inhibition of PI3K-delta is designed to preserve PI3K signaling in normal, non-neoplastic cells. CAL-101 has [EC(50)] = 8nM. TFA approved this drug on July 23, 2014
Technical Data

Purity: >99%
Chemical Formula:C22H18FN7O
Molecular Weight:415.4230
Idelalisib MSDSIdelalisib CoA

IUPAC/Chemical name:(S)-2-(1-((9H-purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Canonical SMILES:

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