Icotinib( Purity > 99% by HPLC)

Product Name: Icotinib
 CAT#: A-2113

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 Synonym: Icotinib; BPI-2009; BPI 2009; BPI2009; Brand name: Conmana. ,

Icotinib Chemical Structure
Icotinibchemical structure

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IUPAC/Chemical name:

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Biological Activity
Icotinib, also known as BPI-2009, is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, is upregulated in a variety of cancer cell types. Icotinib was approved in China in 2011.
Technical Data

Purity: >99%
Chemical Formula:C22H22ClN3O4
Molecular Weight:427.88
Icotinib MSDSIcotinib CoA

IUPAC/Chemical name:N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine
Canonical SMILES:

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