Product Name:


CAT#: A-1052    

Chemical Structure

Price of SAR-245409(XL-147)

The activities of in vitro and in vivo have been approved.

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Biological Activity

XL147 is a selective inhibitor of Class I PI3K isoforms. XL147 reversibly binds to class 1 PI3Ks in an ATP-competitive manner and inhibits the production of PIP3 and activation of the PI3K signaling pathway [1].

Technical Data

M.Wt:      541.03
Purity: >99%
CAS No: 934526-89-3
Storage Conditions : Room temperature, or -20ºC for 2 year.

IUPAC/Chemical name:

[1] G. Shapiro, E. et al. Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post-Meeting Edition).Vol 27, No 15S (May 20 Supplement), 2009: 3500