Product Name:  Defactinib (VS-6063, PF-04554878)   Request PF-04554878
CAT#: A-1079    

Chemical Structure

PF-04554878 chemical structure

Price of PF-04554878

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Biological Activity

Focal adhesion kinase (FAK), a non-receptor tyrosine kinase , orchestrates cell signaling through integrins and growth factor receptors and plays important roles in tumorigenesis. Defactinib is a potent, selective, and orally active FAK inhibitor with demonstrated tolerability and preliminary clinical activity working as a single agent as well as in combination with paclitaxel.
Technical Data

Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
PF-04554878 MSDS PF-04554878 CoA