Product Name: MGCD-516(Sitravatinib)
 CAT#: A-1974

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 Synonym:MGCD-516(Sitravatinib) ,

MGCD-516(Sitravatinib) Chemical Structure
MGCD-516(Sitravatinib)chemical structure

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IUPAC/Chemical name:

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Biological Activity
Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth.
Technical Data

Purity: >99%
Chemical Formula:C33H29F2N5O4S
Molecular Weight:629.68
MGCD-516(Sitravatinib) MSDSMGCD-516(Sitravatinib) CoA

IUPAC/Chemical name:N-(3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Canonical SMILES:O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=C5C(C=C(C6=NC=C(CNCCOC)C=C6)S5)=NC=C4)C(F)=C3

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