Product Name: LY-3214996

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CAT#: A-6069


  Synonym:LY-3214996,

LY-3214996 Chemical Structure LY-3214996 chemical structure


IUPAC/Chemical name: 6,6-dimethyl-2-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-5-(2-morpholinoethyl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-4-one


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Biological Activity
LY-3214996 is a otent and selective, orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity. Upon oral administration, LY3214996 inhibits both ERK 1 and 2, thereby preventing the activation of mitogen-activated protein kinase (MAPK)/ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival.
Technical Data
M.Wt:      453.565
Formula:     C22H27N7O2S
CAS#: 1951483-29-6
Purity: > 99% by HPLC
Storage Conditions: Room temperature for months, or -20ºC for 3 years.

Reference