Product Name: GSK-3326595

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CAT#: A-6068


GSK-3326595 Chemical Structure GSK-3326595 chemical structure

IUPAC/Chemical name: (S)-6-((1-acetylpiperidin-4-yl)amino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)pyrimidine-4-carboxamide

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Biological Activity
GSK-3326595, also known as EPZ015938, is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models.GSK-3326595 halts proliferation and induces apoptosis in numerous solid and hematologic tumor cell lines. It has been shown to have potent anti-tumor activity in vivo in animal models.
Technical Data
M.Wt:      452.559
Formula:     C24H32N6O3
CAS#: 1616392-22-3
Purity: > 99% by HPLC
Storage Conditions: Room temperature for months, or -20ºC for 3 years.