Product Name: CGI-1746Request CGI-1746
CGI-1746 Chemical Structure
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Biological ActivityCGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation.
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