Product Name: BMS-863233.HCl
BMS-863233.HCl Chemical Structure
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BMS-863233.HCl (also called XL-413) is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233.HCl binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.
Mol. Formula: C14H13Cl2N3O22HCl
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
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